Myosin Va

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Myosin Va
  Conformer 1
(PDB) 		1w7j (A)
  Conformer 2
(PDB) 		1w8j (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 163 1.03   104 - 108   153 - 157   183 - 192   224 - 225   229 - 232   236 - 238   435 - 439   442 - 475   490 - 568   636 - 657
2 216 1.67   8 - 103   109 - 152   158 - 182   193 - 198   226 - 228   233 - 235   430 - 434   440 - 441   658 - 693
3 238 0.71   199 - 223   239 - 429   572 - 593
4 82 0.62   476 - 487   695 - 764

Sequence


           ___________________________________________________________________________________________________103__108_____________ 
 1w7j(A) : AASELYTKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGE 
         :                                                                                                                          
 1w8j(A) : AASELYTKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRL----dLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGE 
           ___________________________________________________________________________________________________103__108_____________ 

           __________________________150_____________________________182_____________198_______________________224_228_______238___ 
 1w7j(A) : DIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 
         :                                                                                                                          
 1w8j(A) : DIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVS------nVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRT 
           __________________________150_____________________________182_____________198_______________________224_228_______238___ 

           ________________________________________________________________________________________________________________________ 
 1w7j(A) : YLLEKSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFC 
         :                                                                                                                          
 1w8j(A) : YLLEKSRVVFQAEEERNYHIFYQLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFC 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________426_____434__439_______________________________473________ 
 1w7j(A) : DLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 
         :                                                                                                                          
 1w8j(A) : DLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 
           ______________________________________________________________426_____434__439_______________________________473________ 

           484_________________________________________________________________________________568______________________593________ 
 1w7j(A) : IPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQ------k 
         :                                                                                                                          
 1w8j(A) : IPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQtSKEHKK 
           484_________________________________________________________________________________568______________________593________ 

           ____________________657_________________________________693_____________________________________________________________ 
 1w7j(A) : TVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAG 
         :                                                                                                                          
 1w8j(A) : TVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAG 
           ____________________657_________________________________693_____________________________________________________________ 

           ______________________________________                                                                                   
 1w7j(A) : QVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYMRMRR                                                                                   
         :                                                                                                                          
 1w8j(A) : QVAYLEKIRADK**************************                                                                                   
           ______________________________________                                                                                   

Morph
Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 10.6 0.1 35.7   103 - 105   108 - 109   150 - 158   182 - 195   224 - 226   228 - 236   434 - 435   439 - 442   657 - 658 Bending Region Analysis
1 3 20.1 0.1 26.6   223 - 225   238 - 241   568 - 573   593 - 636 Bending Region Analysis
1 4 16.7 -0.4 94.6   473 - 476   484 - 490 Bending Region Analysis
2 3 27.7 1.0 20.0   198 - 199   426 - 430 Bending Region Analysis
2 4 24.6 -1.9 96.3   693 - 696 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 4

Conformer 2 Contact:
Residue 4 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 2 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 2

Movement classification: Hinge

Conformer 1 Contact:
Residue 2 ———› Residue 4

Conformer 2 Contact:
Residue 4 ———› Residue 2

Movement classification:

No Contacts

PyMOL Script

Download and extract PyMOL PML script file Download