Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		5flf (E)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 164 1.9   539 - 543   564 - 637   641 - 756
2 84 1.32   471 - 538   544 - 563   638 - 640

Sequence


           ________________________________________________________________________538__543_________________563____________________ 
 3gqi(A) : ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEF 
         :                                                                                                                          
 5flf(E) : **PEDPRWELPRDRLVLGKPLg-----QVVLAEAIGLDKDKPNRVTKVAVKMLK--aTEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR------ 
           ________________________________________________________________________538__543_________________563____________________ 

           ___________________________________________________637__________________________________________________________________ 
 3gqi(A) : SFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 
         :                                                                                                                          
 5flf(E) : ---------eQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------------gRLPVKWMAPEALFDGIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 
           ___________________________________________________637__________________________________________________________________ 

           ________________________________________________________________                                                         
 3gqi(A) : VEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                         
         :                                                                                                                          
 5flf(E) : --ELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALT********                                                         
           ________________________________________________________________                                                         

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		17.0
Translation
(A) 		-1.1
Closure
(%) 		98.4
Bending Residues
( green ) 		  538 - 539
  543 - 544
  563 - 564
  637 - 667
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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