DynDom - Protein Domain Motions

Glycogen Synthase 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Glycogen Synthase 1
Conformer 1 (PDB)	1rzu (A)
Conformer 2 (PDB)	3guh (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	251	1.44	3 - 213 216 - 237 244 - 249 252 - 252 462 - 474
2	218	1.68	214 - 215 238 - 243 250 - 251 253 - 461

Sequence

`________________________________________________________________________________________________________________________` `1rzu(A) : MNVLSVSSEIYPLIKTGGLADVVGALPIALEAHGVRTRTLIPGYPAVKAAVTDPVKCFEFTDLLGEKADLLEVQHERLDLLILDAPAYYERSGGPYLGQTGKDYPDNWKRFAALSLAAAR` `:` `3guh(A) : MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTD-AQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAE` `________________________________________________________________________________________________________________________` `__________________________________________________________________________________________213_____________________237___` `1rzu(A) : IGAGVLPGWRPDMVHAHDWQAAMTPVYMRYAETPEIPSLLTIHNIAFQGQFGANIFSKLALPAHAFGMEGIEYYNDVSFLKGGLQTATALSTVSPSYAEEILTAEFGMGLEGVIGSRAHV` `:` `3guh(A) : MASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPA-KSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHRE` `__________________________________________________________________________________________211_____________________235___` `__243___249_____________________________________________________________________________________________________________` `1rzu(A) :` `--LHGIVNGIDADVWNPATDHLIHDNYSAANLKNRALNKKA--VAEHFRIDDDGSPLFCVISRLTWQKGIDLMAEAVDEIVSLGGRLVVLGAGDVALEGALLAAASRHHGRVGVAIGYNE` `:` `3guh(A) :` `GRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDK-VPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHE` `__243___249_____________________________________________________________________________________________________________` `______________________________________________________________________________________________________461_______________` `1rzu(A) : PLSHLMQAGCDAIIIPSRFEPCGLTQLYALRYGCIPVVARTGGLADTVIDANHAALASKAATGVQFSPVTLDGLKQAIRRTVRYYHDPKLWTQMQKLGMKSDVSWEKSAGLYAALYSQLI` `:` `3guh(A) : AFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK` `______________________________________________________________________________________________________462_______________` `_` `1rzu(A) : S` `:` `3guh(A) : *` `_`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	19.8
Translation (A)	0.6
Closure (%)	99.7
Bending Residues ( green )	213 - 216 237 - 239 243 - 244 249 - 253 461 - 462
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file

Download