Glyoxylate Reductase/hydroxypyruvate Reductase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glyoxylate Reductase/hydroxypyruvate Reductase
  Conformer 1
(PDB) 		2wwr (A)
  Conformer 2
(PDB) 		2gcg (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 190 0.39   102 - 298
2 115 0.33   11 - 101   299 - 322

Sequence


           ______________________________________________________________________________________________101_______________________ 
 2wwr(A) : *LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 
         :                                                                                                                          
 2gcg(A) : RLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 
           ______________________________________________________________________________________________101_______________________ 

           ________________________________________________________________________________________________________________________ 
 2wwr(A) : RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVAC-------gLCNKDFFQKMKETAVFINIS 
         :                                                                                                                          
 2gcg(A) : RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________298______________________________                                     
 2wwr(A) : RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELK*                                     
         :                                                                                                                          
 2gcg(A) : RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL                                     
           ___________________________________________________298______________________________                                     

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		2.8
Translation
(A) 		0.1
Closure
(%) 		92.7
Bending Residues
( green ) 		  101 - 102
  298 - 299
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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