Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Metabotropic Glutamate Receptor Subtype 1
  Conformer 1
(PDB) 		1iss (A)
  Conformer 2
(PDB) 		1ewv (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 276 0.7   38 - 208   344 - 477
2 168 0.7   209 - 343   478 - 510

Sequence


           ________________________________________________________________________________________________________________________ 
 1iss(A) : RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLIkPIAGVIGPGSSSVAIQVQNLLQLFDI 
         :                                                                                                                          
 1ewv(A) : RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIR----kPIAGVIGPGSSSVAIQVQNLLQLFDI 
           ________________________________________________________________________________________________________________________ 

           _________________________208____________________________________________________________________________________________ 
 1iss(A) : PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL 
         :                                                                                                                          
 1ewv(A) : PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL 
           _________________________208____________________________________________________________________________________________ 

           ________________________________________343_____________________________________________________________________________ 
 1iss(A) : SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAM 
         :                                                                                                                          
 1ewv(A) : SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAM 
           ________________________________________343_____________________________________________________________________________ 

           ______________________________________________________477___________________________________                             
 1iss(A) : AHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                             
         :                                                                                                                          
 1ewv(A) : AHGLQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                             
           ______________________________________________________477___________________________________                             

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		22.7
Translation
(A) 		-0.5
Closure
(%) 		100.0
Bending Residues
( green ) 		  208 - 209
  343 - 344
  477 - 481
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download