Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mitogen-Activated Protein Kinase 14
  Conformer 1
(PDB) 		3hv7 (A)
  Conformer 2
(PDB) 		3iw5 (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 188 0.7   79 - 83   109 - 164   187 - 317
2 113 0.5   8 - 78   84 - 108   165 - 166   332 - 349

Sequence


           _______________________________________________________________________78___83______________________108_________________ 
 3hv7(A) : *RPTFYRQELNKTIWEVPERYQNLSPVGS-gSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNI----kLTDD 
         :                                                                                                                          
 3iw5(A) : ERPTFYRQELNKTIWEVPERYQNLSPVGSyGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKSQKLTDD 
           _______________________________________________________________________78___83______________________108_________________ 

           ____________________________________164_________________________________________________________________________________ 
 3hv7(A) : HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLvATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESAR 
         :                                                                                                                          
 3iw5(A) : HVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDSELKILDFGL-aTRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESAR 
           ____________________________________164_________________________________________________________________________________ 

           __________________________________________________________317____________________________________                        
 3hv7(A) : NYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP*                        
         :                                                                                                                          
 3iw5(A) : NYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSLESRDLLIDEWKSLTYDEVISFVPPPL                        
           __________________________________________________________317____________________________________                        

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		5.7
Translation
(A) 		0.3
Closure
(%) 		95.9
Bending Residues
( green ) 		  78 - 79
  83 - 84
  108 - 121
  164 - 187
  317 - 333
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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