Myosin Heavy Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Myosin Heavy Chain
  Conformer 1
(PDB) 		1dfl (A)
  Conformer 2
(PDB) 		1kk7 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 80 1.22   493 - 509   706 - 772
2 617 2.36   7 - 492   515 - 703
3 61 1.16   773 - 833

Sequence


           ________________________________________________________________________________________________________________________ 
 1dfl(A) : FSDPDFQYLAVDqT----AAFDGKKNCWVPDEKEGFASAEIQSSKGDEITVKIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYTYSGLFCIAVNPYR 
         :                                                                                                                          
 1kk7(A) : FSDPDFQYLAVDRKKLMKaAFDGKKNCWVPDEKEGFASAEIQSSKGDEITVKIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYTSGLIYTYSGLFCIAVNPYR 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1dfl(A) : RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKV----------------eDQIIQANPVLEAYGNAKTTRNNNSSRFGKFIRIH 
         :                                                                                                                          
 1kk7(A) : RLPIYTDSVIAKYRGKRKTEIPPHLFSVADNAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKVACAVKKKeEASDKgSLEDQIIQANPVLEAYGNAKTTRNNNSSRFGKFIRIH 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1dfl(A) : FGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSNAIPELNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKFKQRPREE 
         :                                                                                                                          
 1kk7(A) : FGPTGKIAGADIETYLLEKSRVTYQQSAERNYHIFYQICSNAIPELNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKFK--pREE 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________________________________________491_ 
 1dfl(A) : QAESDGTAEAEKVAFLCGINAGDLLKALLKPKv-----TKGQNMNQVVNSVGALAKSLYDRMFNWLVRRVNKTLDTKAKRNYYIGVLDIAGFEIFDFNSFEQLCINYTNERLQQFFNHHM 
         :                                                                                                                          
 1kk7(A) : QAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVeMVTKGQNMNQVVNSVGALAKSLYDRMFNWLVRRVNKTLDTKA-rNYYIGVLDIAGFEIFDFNSFEQLCINYTNERLQQFFNHHM 
           ____________________________________________________________________________________________________________________491_ 

           ____________507_________________________________________________________________________________________________________ 
 1dfl(A) : FILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGWLEKNKDPINENVVALLGA 
         :                                                                                                                          
 1kk7(A) : FILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMGILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKPTRPNQGPAHFELHHYAGNVPYSITGWLEKNKDPINENVVALLGA 
           ____________507_________________________________________________________________________________________________________ 

           _______________________________________________________________693______________________________________________________ 
 1dfl(A) : SKEPLVAE-------qTISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICRKGFPSRLIYSEFKQRYSILAPNAIPdGKTVSEKILAGLQMDPA 
         :                                                                                                                          
 1kk7(A) : SKEPLVAELFKAPEEqTISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVLEGIRICRKGFPSRLIYSEFKQRYSILAPNAIPdGKTVSEKILAGLQMDPA 
           _______________________________________________________________693______________________________________________________ 

           __________________772_________________________________________________________________                                   
 1dfl(A) : EYRLGTTKVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQWWKLYSKVKP**                                   
         :                                                                                                                          
 1kk7(A) : EYRLGTTKVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGLSVIQRNIRKWLVLRNWQWWKLYSKVKPLL                                   
           __________________772_________________________________________________________________                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		72.2
Translation
(A) 		-0.6
Closure
(%) 		23.2
Bending Residues
( green ) 		  491 - 494
  507 - 515
  693 - 706
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		21.1
Translation
(A) 		-0.3
Closure
(%) 		17.2
Bending Residues
( green ) 		  772 - 773
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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