Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Pyruvate Kinase
  Conformer 1
(PDB) 		1e0t (A)
  Conformer 2
(PDB) 		1e0t (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 348 0.33   3 - 72   166 - 166   168 - 468
2 94 0.26   73 - 165   167 - 167

Sequence


           __________________________________________________________________68____________________________________________________ 
 1e0t(A) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
         :                                                                                                                          
 1e0t(C) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
           __________________________________________________________________68____________________________________________________ 

           _________________________________________164____________________________________________________________________________ 
 1e0t(A) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
         :                                                                                                                          
 1e0t(C) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
           _________________________________________164____________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1e0t(A) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATMrPTDAEAGDVANAILDGTDAVMLSGEpLEAVSIMATICERTDRVMNSRLEiTEAVCRGAVETAEKLDAPLIVVATQGGKSA 
         :                                                                                                                          
 1e0t(C) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATMrPTDAEAGDVANAILDGTDAVMLSGEpLEAVSIMATICERTDRVMNSRLEiTEAVCRGAVETAEKLDAPLIVVATQGGKSA 
           ________________________________________________________________________________________________________________________ 

           ______________________________________________________________________________________                                   
 1e0t(A) : RAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                                   
         :                                                                                                                          
 1e0t(C) : RAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                                   
           ______________________________________________________________________________________                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		10.0
Translation
(A) 		0.6
Closure
(%) 		13.4
Bending Residues
( green ) 		  68 - 73
  164 - 171
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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