DynDom - Protein Domain Motions

Receptor-Type Tyrosine-Protein Phosphatase Epsilon

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Receptor-Type Tyrosine-Protein Phosphatase Epsilon
Conformer 1 (PDB)	2jjd (B)
Conformer 2 (PDB)	2jjd (D)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	281	0.28	114 - 406
2	254	0.26	425 - 689

Sequence

`________________________________________________________________________________________________________________________` `2jjd(B) : KYFPIPVEHLEEEIRIRSkQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLgIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTN` `:` `2jjd(D) : *YFPIPVEHLEEEIRIR-kQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLgIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTN` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2jjd(B) : LKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPkAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKV` `:` `2jjd(D) : LKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPkAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKV` `________________________________________________________________________________________________________________________` `_________________________________________405____________________________________________________________________________` `2jjd(B) : DVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSgLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMyTDYINASFIDGYRQKDYFIATQGPLA` `:` `2jjd(D) : DVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSgLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMyTDYINASFIDGYRQKDYFIATQGPLA` `_________________________________________405____________________________________________________________________________` `________________________________________________________________________________________________________________________` `2jjd(B) : HTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNgEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHC` `:` `2jjd(D) : HTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNgEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHC` `________________________________________________________________________________________________________________________` `_____________________________________________________________` `2jjd(B) : SAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID` `:` `2jjd(D) : SAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID` `_____________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	8.3
Translation (A)	0.0
Closure (%)	43.7
Bending Residues ( green )	405 - 426
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

Download and extract PyMOL PML script file

Download