DynDom - Protein Domain Motions

Sumo-Activating Enzyme Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Sumo-Activating Enzyme Subunit 2
Conformer 1 (PDB)	3kyc (B)
Conformer 2 (PDB)	3kyd (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	326	1.51	7 - 167 382 - 546
2	146	2.4	168 - 381

Sequence

`________________________________________________________________________________________________________________________` `3kyc(B) : RGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARN` `:` `3kyd(B) : SRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARN` `________________________________________________________________________________________________________________________` `______________________________________164_______________________________________________________________________________` `3kyc(B) : HVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWiKRISTKEWAKSTGYDPVKLFTKLFK` `:` `3kyd(B) : HVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLF-------------------------tKEWAKSTGYDPVKLFTKLFK` `______________________________________164_______________________________________________________________________________` `_________________________________________________________________________________________________________381____________` `3kyc(B) : DDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGlGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAV` `:` `3kyd(B) : DDIRYLLTMDKLWRKRKPPVPLDWAEVQSQ-----dQQVLDVKSYARLFSKSIETLRVHLAEK--------dKDDPSAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAV` `_________________________________________________________________________________________________________381____________` `________________________________________________________________________________________________________________________` `3kyc(B) : IAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRN` `:` `3kyd(B) : IAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRN` `________________________________________________________________________________________________________________________` `_____________________________________________________________________` `3kyc(B) : GSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGeRSRKRKLDEKENLSAKRSRIEQKEELDDVIALD` `:` `3kyd(B) : GSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVG*********************************` `_____________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	128.8
Translation (A)	2.4
Closure (%)	41.1
Bending Residues ( green )	164 - 176 381 - 386
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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