Immunoglobulin 48G7 Germline Fab

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Immunoglobulin 48G7 Germline Fab
  Conformer 1
(PDB) 		1gaf (L)
  Conformer 2
(PDB) 		1l7i (L)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 107 0.42   11 - 12   105 - 209
2 100 1.14   3 - 10   13 - 104

Sequence


           ________10___________________________________________________________________________________________104________________ 
 1gaf(L) : DIQMTQSPSSLSASLGERVSLTCRASQEINGYLGWLQQKPDGTIKRLIYAASTLHSGVPKRFSGSRSGSDYSLTISSLESEDFADYYCLQYASYPRTFGGGTKVEIKRTVAAPSVFIFPP 
         :                                                                                                                          
 1l7i(L) : DIQMTQSPSSLSASVGDRVTITCKASQDVSIGVAWYQQKPGKAPKLLIYSASYRYTGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYYIYPYTFGQGTKVEIKRTVAAPSVFIFPP 
           ________10___________________________________________________________________________________________104________________ 

           ______________________________________________________________________________________________                           
 1gaf(L) : SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC                           
         :                                                                                                                          
 1l7i(L) : SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC                           
           ______________________________________________________________________________________________                           

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		19.9
Translation
(A) 		-0.7
Closure
(%) 		89.3
Bending Residues
( green ) 		  10 - 13
  104 - 105
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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