Gamma-Aminobutyric Acid Receptor Subunit Gamma-2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gamma-Aminobutyric Acid Receptor Subunit Gamma-2
  Conformer 1
(PDB) 		6hup (C)
  Conformer 2
(PDB) 		6hug (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 220 0.6   28 - 229   244 - 246   286 - 300
2 106 0.68   230 - 243   247 - 285   301 - 434

Sequence


           ________________________________________________________________________________________________________________________ 
 6hup(C) : DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 
         :                                                                                                                          
 6hug(C) : DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________________________229___________243______________________ 
 6hup(C) : TIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPAR 
         :                                                                                                                          
 6hug(C) : TIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPAR 
           _________________________________________________________________________________229___________243______________________ 

           ____________280_________________300_______________________________________________________                               
 6hup(C) : TSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRrIAKMDSYARIFFPTAFCLFNLVYWVSYLYL                               
         :                                                                                                                          
 6hug(C) : TSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRrIAKMDSYARIFFPTAFCLFNLVYWVSYLYL                               
           ____________280_________________300_______________________________________________________                               

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.6
Translation
(A) 		0.4
Closure
(%) 		35.0
Bending Residues
( green ) 		  229 - 230
  243 - 247
  280 - 297
  300 - 301
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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