Importin Subunit Alpha-3

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Importin Subunit Alpha-3
  Conformer 1
(PDB) 		6wx8 (A)
  Conformer 2
(PDB) 		6wx7 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 228 1.0   243 - 248   262 - 483
2 187 1.88   69 - 242   249 - 261

Sequence


           ________________________________________________________________________________________________________________________ 
 6wx8(A) : RVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIG 
         :                                                                                                                          
 6wx7(A) : GTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________242_246____________261_________________________________________ 
 6wx8(A) : DGPQCRDYVISLGVVKPLLSFIS-PSIPIT---FLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQT 
         :                                                                                                                          
 6wx7(A) : DGSAFRDLVIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVT 
           _________________________________________________________251_255____________270_________________________________________ 

           ________________________________________________________________________________________________________________________ 
 6wx8(A) : AALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTV 
         :                                                                                                                          
 6wx7(A) : PALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSA 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________________________                                                       
 6wx8(A) : KDAQVVQVVLDGLSNILKMAED--EAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFF*                                                       
         :                                                                                                                          
 6wx7(A) : KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHENESVYKASLNLIEKYFS                                                       
           __________________________________________________________________                                                       

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		14.3
Translation
(A) 		0.3
Closure
(%) 		34.7
Bending Residues
( green ) 		  242 - 244
  246 - 249
  261 - 262
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

Download and extract PyMOL PML script file Download