Sam-Dependent Methyltransferases

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Sam-Dependent Methyltransferases
  Conformer 1
(PDB) 		4d7k (A)
  Conformer 2
(PDB) 		4d7k (F)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 178 0.71   13 - 168   292 - 311   335 - 335   337 - 337
2 153 0.52   169 - 291   312 - 334   336 - 336   338 - 343

Sequence


           ________________________________________________________________________________________________________________________ 
 4d7k(A) : RTAAQRLYQYNVDLKVAFVLYAVAKLHLPDLLADGPRTTADLAAATGSDPSRLRRLLRAAAGADALREVPEDSFELAPMGDLLRSGHPRSMRGMTTFFAEPDVLAAYGDLVESVRTGVPA 
         :                                                                                                                          
 4d7k(F) : RTAAQRLYQYNVDLKVAFVLYAVAKLHLPDLLADGPRTTADLAAATGSDPSRLRRLLRAAAGADALREVPEDSFELAPMGDLLRSGHPRSMRGMTTFFAEPDVLAAYGDLVESVRTGVPA 
           ________________________________________________________________________________________________________________________ 

           ___________________________________168__________________________________________________________________________________ 
 4d7k(A) : FQLRHREPLYDFLARPQHKEVRDEFDAAMVEFGQYFADDFLTSFDFGRFTRFADIGGGRGQFLAGVLTAVPSSTGVLVDGPAVAASAHKFLASQNLTERVEVRIGDFFDVLPTGCDAYVL 
         :                                                                                                                          
 4d7k(F) : FQLRHREPLYDFLARPQHKEVRDEFDAAMVEFGQYFADDFLTSFDFGRFTRFADIGGGRGQFLAGVLTAVPSSTGVLVDGPAVAASAHKFLASQNLTERVEVRIGDFFDVLPTGCDAYVL 
           ___________________________________168__________________________________________________________________________________ 

           ______________________________________291______________308_______________________334_____________                        
 4d7k(A) : RGVLEDWADADAVRLLVRIRQAMGDAPEARLLILDSVIGETGELGKVLDLDMLVLVEGEHRTRAQWDDLLARAGFDIVGIHPAGDVWAVIECRGT**                        
         :                                                                                                                          
 4d7k(F) : RGVLEDWADADAVRLLVRIRQAMGDAPEARLLILDSVIGETGELGKVLDLDMLVLVEGEHRTRAQWDDLLARAGFDIVGIHPAGDVWAVIECRGTAG                        
           ______________________________________291______________308_______________________334_____________                        

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.1
Translation
(A) 		-0.6
Closure
(%) 		20.9
Bending Residues
( green ) 		  168 - 173
  291 - 292
  308 - 312
  334 - 338
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download