Eukaryotic Initiation Factor 4A-I

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Eukaryotic Initiation Factor 4A-I
  Conformer 1
(PDB) 		2zu6 (A)
  Conformer 2
(PDB) 		2vsx (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 168 2.66   26 - 237
2 149 1.78   238 - 399

Sequence


           ________________________________________________________________________________________________________________________ 
 2zu6(A) : *****************************MEGVIESNWNEaILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 
         :                                                                                                                          
 2vsx(A) : QIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIg----- 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________________________237________________________ 
 2zu6(A) : AEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLD 
         :                                                                                                                          
 2vsx(A) : -------LRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYE 
           _____________________________________________________________________________________________225________________________ 

           ________________________________________________________________________________________________________________________ 
 2zu6(A) : TLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMH-------rDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGkGVAINMVTEEDKR 
         :                                                                                                                          
 2vsx(A) : CLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGR-----kGVAINFVTNEDVG 
           ________________________________________________________________________________________________________________________ 

           _______________________                                                                                                  
 2zu6(A) : TLRDIETFYNTSIEEMPLN****                                                                                                  
         :                                                                                                                          
 2vsx(A) : AMRELEKFYSTQIEELPSDIATL                                                                                                  
           _______________________                                                                                                  

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		39.1
Translation
(A) 		-1.0
Closure
(%) 		21.0
Bending Residues
( green ) 		  237 - 238
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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