Gamma-Aminobutyric Acid Receptor Subunit Alpha-1,gamma- Aminobutyric Acid Receptor Subunit Alpha-1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Gamma-Aminobutyric Acid Receptor Subunit Alpha-1,gamma- Aminobutyric Acid Receptor Subunit Alpha-1
  Conformer 1
(PDB) 		6hup (A)
  Conformer 2
(PDB) 		6hug (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 196 0.7   15 - 144   151 - 186   192 - 221
2 144 0.59   145 - 150   187 - 191   222 - 416

Sequence


           ________________________________________________________________________________________________________________________ 
 6hup(A) : ***TVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLY 
         :                                                                                                                          
 6hug(A) : DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLY 
           ________________________________________________________________________________________________________________________ 

           ____________144___150_________________________________186________________________________221____________________________ 
 6hup(A) : TMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNR 
         :                                                                                                                          
 6hug(A) : TMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNR 
           ____________144___150_________________________________186________________________________221____________________________ 

           ___________________________________________________________________________________________________________              
 6hup(A) : ESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSkTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNR              
         :                                                                                                                          
 6hug(A) : ESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSkTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNR              
           ___________________________________________________________________________________________________________              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.0
Translation
(A) 		-0.7
Closure
(%) 		36.0
Bending Residues
( green ) 		  144 - 145
  150 - 151
  186 - 192
  221 - 222
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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