Glyoxylate Reductase/hydroxypyruvate Reductase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glyoxylate Reductase/hydroxypyruvate Reductase
  Conformer 1
(PDB) 		2gcg (A)
  Conformer 2
(PDB) 		2cuk (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 183 1.03   107 - 296
2 124 1.38   9 - 106   297 - 325

Sequence


           ___________________________________________________________________________________________________106__________________ 
 2gcg(A) : RLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 
         :                                                                                                                          
 2cuk(A) : **MRVLVTRTLPGKALDRL-RERGLEVEV-HRGLFLPKAELLKRVEGAVGLIPTVEDRIDAEVMDRA-KGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVAR 
           ____________________________________________________________________________________________________97__________________ 

           ________________________________________________________________________________________________________________________ 
 2gcg(A) : RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 
         :                                                                                                                          
 2cuk(A) : RVVEGAAYARDGLWKAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGM-RVVYHARTPKP-----LPYPFLSLEELLKEADVVSLHTPLTPETHRLLNRERLFAMKRGAILLNTA 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________296________________________________                                     
 2gcg(A) : RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL                                     
         :                                                                                                                          
 2cuk(A) : RGALVDTEALVEAL-RGHLFGAGLDVTDPEPLPPGHPLYALPNAVITPHIGSAGRTTRERMAEVAVENLLAVLEGREPPNPVV*                                     
           _________________________________________________280________________________________                                     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.7
Translation
(A) 		0.1
Closure
(%) 		100.0
Bending Residues
( green ) 		  106 - 107
  296 - 297
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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