DynDom - Protein Domain Motions

Phosphoenolpyruvate Carboxykinase, Cytosolic [Gtp]

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate Carboxykinase, Cytosolic [Gtp]
Conformer 1 (PDB)	2qew (A)
Conformer 2 (PDB)	2qey (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	555	0.31	11 - 283 287 - 289 293 - 438 441 - 513 519 - 522 536 - 548 553 - 556 572 - 620
2	45	0.47	284 - 286 290 - 292 439 - 440 514 - 518 523 - 535 549 - 552 557 - 571

Sequence

`________________________________________________________________________________________________________________________` `2qew(A) : PQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDF` `:` `2qey(A) : PQLHNGLDFSAKVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDF` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2qew(A) : EKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLG` `:` `2qey(A) : EKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLG` `________________________________________________________________________________________________________________________` `______________________________________283_______________________________________________________________________________` `2qew(A) : KKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAE` `:` `2qey(A) : KKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAE` `______________________________________283_______________________________________________________________________________` `_________________________________________________________________________438____________________________________________` `2qew(A) : TSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEAgKVIMHDPFAMRPFFGYN` `:` `2qey(A) : TSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSE---vIMhDPFAMRPFFGYN` `_________________________________________________________________________438____________________________________________` `_____________________513__518______________535__________548_552_556___________570_______________________________________` `2qew(A) : FGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIE` `:` `2qey(A) : FGKYLAHWLSMAHRPAAKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLGDVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIE` `_____________________513__518______________535__________548_552_556___________570_______________________________________` `_____________` `2qew(A) : RELRALKQRISQM` `:` `2qey(A) : RELRALKQRISQM` `_____________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	2.7
Translation (A)	-0.2
Closure (%)	96.7
Bending Residues ( green )	283 - 293 438 - 441 513 - 514 518 - 523 535 - 536 548 - 549 552 - 553 556 - 557 570 - 572
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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