Protein Disulfide-Isomerase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Protein Disulfide-Isomerase
  Conformer 1
(PDB) 		4ekz (A)
  Conformer 2
(PDB) 		4el1 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 107 1.08   236 - 356
2 100 0.69   136 - 235
3 120 0.75   357 - 476
4 114 0.89   20 - 133

Sequence


           ________________________________________________________________________________________________________________________ 
 4ekz(A) : HHSSGLEVLFQGPGSDAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREA 
         :                                                                                                                          
 4el1(A) : ***************DAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREA 
           ________________________________________________________________________________________________________________________ 

           _______132____________________________________________________________________________________________________235_______ 
 4ekz(A) : DDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIE--- 
         :                                                                                                                          
 4el1(A) : DDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTE 
           _______132____________________________________________________________________________________________________235_______ 

           _____________________________________________________________________________________________________________356________ 
 4ekz(A) : --aPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEmTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDW 
         :                                                                                                                          
 4el1(A) : QTAPKIF-----tHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLIT--mTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDW 
           _____________________________________________________________________________________________________________356________ 

           __________________________________________________________________________________________________________________       
 4ekz(A) : DKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGA       
         :                                                                                                                          
 4el1(A) : DKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGA       
           __________________________________________________________________________________________________________________       

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 37.1 0.4 1.0   235 - 236 Bending Region Analysis
1 3 48.4 -1.2 69.4   356 - 357 Bending Region Analysis
4 2 12.0 -3.1 26.2   132 - 138 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 4 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 4

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download