Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Pyruvate Kinase
  Conformer 1
(PDB) 		1pky (A)
  Conformer 2
(PDB) 		1e0t (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 346 0.47   4 - 69   164 - 166   168 - 468
2 95 0.42   70 - 163   167 - 167

Sequence


           ___________________________________________________________________69___________________________________________________ 
 1pky(A) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
         :                                                                                                                          
 1e0t(A) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
           ___________________________________________________________________69___________________________________________________ 

           ________________________________________163_____________________________________________________________________________ 
 1pky(A) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
         :                                                                                                                          
 1e0t(A) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
           ________________________________________163_____________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1pky(A) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATMMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEkLRITEAVCRGAVETA 
         :                                                                                                                          
 1e0t(A) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATM---------rPTDAEAGDVANAILDGTDAVMLSGE------pLEAVSIMATICERTDRVMNSRLE---iTEAVCRGAVETA 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________                 
 1pky(A) : EKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                 
         :                                                                                                                          
 1e0t(A) : EKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                 
           ________________________________________________________________________________________________________                 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		5.0
Translation
(A) 		0.3
Closure
(%) 		96.0
Bending Residues
( green ) 		  69 - 71
  163 - 164
  166 - 168
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download