DynDom - Protein Domain Motions

Succinyl-Coa:3-Ketoacid-Coenzyme A Transferase 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Succinyl-Coa:3-Ketoacid-Coenzyme A Transferase 1
Conformer 1 (PDB)	3dlx (A)
Conformer 2 (PDB)	3dlx (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	269	0.3	42 - 46 52 - 77 85 - 99 108 - 108 110 - 117 135 - 158 188 - 285 314 - 320 326 - 397 423 - 435
2	28	0.31	47 - 51 78 - 84 100 - 101 109 - 109 122 - 134
3	119	0.42	161 - 161 299 - 313 321 - 325 398 - 414 436 - 516

Sequence

`_____46___51________________________77_____84_____________99_______________117______________134_____________________158_` `3dlx(A) : TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT` `:` `3dlx(B) : TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPT` `_____46___51________________________77_____84_____________99_______________117______________134_____________________158_` `________________________________________________________________________________________________________________________` `3dlx(A) : GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI` `:` `3dlx(B) : GYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRI` `________________________________________________________________________________________________________________________` `_283_________________313____320__________________________________________________________________________397____________` `3dlx(A) : ERLSIRKpGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGD` `:` `3dlx(B) : ERLSIR---dDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGD` `_283_________________313____320__________________________________________________________________________397____________` `__414__________________435____________________________________________________________________________________` `3dlx(A) : LANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIA` `:` `3dlx(B) : LANWMIPGK-vKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQI*` `__414__________________435____________________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	2.8
Translation (A)	0.0
Closure (%)	38.0
Bending Residues ( green )	46 - 47 51 - 52 77 - 78 84 - 85 99 - 110 117 - 122 134 - 135
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	4.4
Translation (A)	0.0
Closure (%)	99.4
Bending Residues ( green )	158 - 189 283 - 299 313 - 314 320 - 326 397 - 398 414 - 423 435 - 436
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Shear

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