DynDom - Protein Domain Motions

Sucrose Isomerase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Sucrose Isomerase
Conformer 1 (PDB)	2pwh (A)
Conformer 2 (PDB)	4h2c (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	348	0.56	5 - 54 74 - 74 77 - 97 194 - 194 254 - 254 278 - 314 316 - 316 319 - 554
2	202	0.54	55 - 73 75 - 76 98 - 193 195 - 253 255 - 277 315 - 315 317 - 318

Sequence

`___________________________________________________54_________________73______________________97________________________` `2pwh(A) : PGAPWWKSAVFYQVYPRSFKDTNGDGIGDFKGLTEKLDYLKGLGIDAIWINPHYASPNTDNGYDISDYREVMKEYGTMEDFDRLMAELKKRGMRLMVDVVINHSSDQHEWFKSSRASKDN` `:` `4h2c(A) : *GAPWWKSAVFYQVYPRSFKDTNGDGIGDFKGLTEKLDYLKGLGIDAIWINPHYASPNTDNGYDISDYREVMKEYGTMEDFDRLMAELKKRGMRLMVDVVINHSSDQHEWFKSSRASKDN` `___________________________________________________54_________________73______________________97________________________` `_____________________________________________________________________193________________________________________________` `2pwh(A) : PYRDYYFWRDGKDGHEPNNYPSFFGGSAWEKDPVTGQYYLHYFGRQQPDLNWDTPKLREELYAMLRFWLDKGVSGMRFDTVATYSKTPGFPDLTPEQMKNFAEAYTQGPNLHRYLQEMHE` `:` `4h2c(A) : PYRDYYFWRDGKDGHEPNNYPSFFGGSAWEKDPVTGQYYLHYFGRQQPDLNWDTPKLREELYAMLRFWLDKGVSGMRFDTVATYSKTPGFPDLTPEQMKNFAEAYTQGPNLHRYLQEMHE` `_____________________________________________________________________193________________________________________________` `_________253____________________276______________________________309____________________________________________________` `2pwh(A) : KVFDHYDAVTAGEIFGAPLNQVPLFIDSRRKELDMAFTFDLIRYDRALDRWHTIPRTLADFRQTIDKVDAIAGEYGWNTFFLGNHDNPRAVSHFGDDRPQWREASAKALATVTLTQRGTP` `:` `4h2c(A) : KVFDHYDAVTAGEIFGAPLNQVPLFIDSRRKELDMAFTFDLICYDRALDRWHTIPRTLADFRQTIDKVDAIAGEYGWNTFFLGNHDNPRAVSHFGDDRPQWREASAKALATVTLTQRGTP` `_________253____________________276______________________________309____________________________________________________` `________________________________________________________________________________________________________________________` `2pwh(A) : FIFQGDELGMTNYPFKTLQDFDDIEVKGFFQDYVETGKATAEELLTNVALTSRDNARTPFQWDDSANAGFTTGKPWLKVNPNYTEINAAREIGDPKSVYSFYRNLISIRHETPALSTGSY` `:` `4h2c(A) : FIFQGDELGMTNYPFKTLQDFDDIEVKGFFQDYVETGKATAEELLTNVALTSRDNARTPFQWDDSANAGFTTGKPWLKVNPNYTEINAAREIGDPKSVYSFYRNLISIRHETPALSTGSY` `________________________________________________________________________________________________________________________` `____________________________________________________________________________` `2pwh(A) : RDIDPSNADVYAYTRSQDGETYLVVVNFKAEPRSFTLPDGMHIAETLIESSSPAAPAAGAASLELQPWQSGIYKVK` `:` `4h2c(A) : RDIDPSNADVYAYTRSQDGETYLVVVNFKAEPRSFTLPDGMHIAETLIESSSPAAPAAGAASLELQPWQSGIYKVK` `____________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	11.2
Translation (A)	0.6
Closure (%)	93.8
Bending Residues ( green )	54 - 55 73 - 77 97 - 99 193 - 197 253 - 255 276 - 278 309 - 319
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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