DynDom - Protein Domain Motions

Uncharacterized Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Uncharacterized Protein
Conformer 1 (PDB)	4x7m (A)
Conformer 2 (PDB)	4x7p (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	300	0.66	3 - 16 25 - 255 260 - 282 284 - 284 286 - 304 403 - 406 425 - 427 479 - 480 488 - 490
2	189	0.44	17 - 24 256 - 259 283 - 283 285 - 285 305 - 402 407 - 424 428 - 478 481 - 487 491 - 491

Sequence

`______________16_____23_________________________________________________________________________________________________` `4x7m(A) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTRTYI` `:` `4x7p(A) : MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTGTYI` `______________16_____23_________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `4x7m(A) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `:` `4x7p(A) : AYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK` `________________________________________________________________________________________________________________________` `__________253__________________________282___________________304________________________________________________________` `4x7m(A) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `:` `4x7p(A) : NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSV` `__________253__________________________282___________________304________________________________________________________` `_______________________________________402_406_______________424___________________________________________________478__` `4x7m(A) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `:` `4x7p(A) : KDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST` `_______________________________________402_406_______________424___________________________________________________478__` `____487______` `4x7m(A) : ESILEKWLNLFNS` `:` `4x7p(A) : ESILEKWLNLFNS` `____487______`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	6.8
Translation (A)	0.4
Closure (%)	52.7
Bending Residues ( green )	16 - 19 23 - 25 253 - 262 282 - 286 304 - 305 402 - 403 406 - 413 424 - 425 427 - 428 478 - 484 487 - 491
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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