Mast/stem Cell Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mast/stem Cell Growth Factor Receptor
  Conformer 1
(PDB) 		2ec8 (A)
  Conformer 2
(PDB) 		2e9w (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 108 1.07   225 - 226   305 - 410
2 264 1.07   35 - 224   227 - 304
3 75 1.67   411 - 503

Sequence


           ________________________________________________________________________________________________________________________ 
 2ec8(A) : LCVLLLLLePSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVT 
         :                                                                                                                          
 2e9w(A) : ********EPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDSDTLVRCPLTDPEVT 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________224________________________________________ 
 2ec8(A) : NYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVD----sVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHH 
         :                                                                                                                          
 2e9w(A) : SYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHH 
           _____________________________________________________________________________224________________________________________ 

           _____________________________________304________________________________________________________________________________ 
 2ec8(A) : GDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKG 
         :                                                                                                                          
 2e9w(A) : GDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKG 
           _____________________________________304________________________________________________________________________________ 

           _______________________410_____________________________________________________________________________________________  
 2ec8(A) : TEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFC------vLPVDVQTLNSgPPFGKLVVQSSIDSSAFKH-----cKAYNDVGKTSAYFNFAF  
         :                                                                                                                          
 2e9w(A) : TEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGcSASVLPVDVQTLNSS--fGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFA*  
           _______________________410_____________________________________________________________________________________________  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		22.0
Translation
(A) 		0.1
Closure
(%) 		44.6
Bending Residues
( green ) 		  224 - 227
  304 - 305
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		28.5
Translation
(A) 		0.3
Closure
(%) 		83.7
Bending Residues
( green ) 		  410 - 411
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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