DynDom - Protein Domain Motions

Phosphomannomutase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphomannomutase
Conformer 1 (PDB)	1k2y (X)
Conformer 2 (PDB)	1p5g (X)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	121	0.61	259 - 263 266 - 266 280 - 293 300 - 307 309 - 320 323 - 327 366 - 379 388 - 421 430 - 456 461 - 461
2	309	0.67	11 - 258 264 - 265 267 - 279 294 - 299 308 - 308 321 - 322 328 - 365
3	20	0.71	380 - 387 422 - 429 457 - 460

Sequence

`________________________________________________________________________________________________________________________` `1k2y(X) : KAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGAHNPPDYNGFKIVVAGE` `:` `1p5g(X) : ****LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTG-hNPPDYNGFKIVVAGE` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `1k2y(X) : TLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGD` `:` `1p5g(X) : TLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGD` `________________________________________________________________________________________________________________________` `___________258_________________278____________293___299____306___________320__________________________________________36` `1k2y(X) : GDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVF` `:` `1p5g(X) : GDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVF` `___________258_________________278____________293___299____306___________320__________________________________________36` `5___________379_____387_______________________________421_____429_______________________455__460___` `1k2y(X) : SAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `:` `1p5g(X) : SAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `5___________379_____387_______________________________421_____429_______________________455__460___`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	9.6
Translation (A)	-0.4
Closure (%)	99.7
Bending Residues ( green )	258 - 267 278 - 280 293 - 294 299 - 300 306 - 309 320 - 329 365 - 366
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	5.7
Translation (A)	-0.7
Closure (%)	93.1
Bending Residues ( green )	379 - 380 387 - 388 421 - 422 429 - 430 455 - 457 460 - 461
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Shear

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