Transthyretin

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Transthyretin
  Conformer 1
(PDB) 		5cn3 (A)
  Conformer 2
(PDB) 		3tct (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 89 0.18   13 - 18   25 - 74   90 - 115   117 - 123
2 22 0.24   19 - 24   75 - 89   116 - 116

Sequence


           _______18____24________________________________________________74_____________89_______________________115__________     
 5cn3(A) : CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP     
         :                                                                                                                          
 3tct(A) : *PLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSEsGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP     
           _______18____24________________________________________________74_____________89_______________________115__________     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		4.0
Translation
(A) 		-0.1
Closure
(%) 		99.9
Bending Residues
( green ) 		  18 - 19
  24 - 25
  74 - 75
  89 - 90
  115 - 118
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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