Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3kxx (D)
  Conformer 2
(PDB) 		5vnd (B)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 253 1.82   465 - 640   662 - 757
2 21 4.43   641 - 661

Sequence


           ________________________________________________________________________________________________________________________ 
 3kxx(D) : HMAGVSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQA 
         :                                                                                                                          
 5vnd(B) : ****VSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVECASKGNLREYLQA 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________639___________________661_____________________________________________ 
 3kxx(D) : --------lSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV 
         :                                                                                                                          
 5vnd(B) : RRPPGeEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV 
           __________________________________________________639___________________661_____________________________________________ 

           ___________________________________________________________                                                              
 3kxx(D) : EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS***                                                              
         :                                                                                                                          
 5vnd(B) : EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE                                                              
           ___________________________________________________________                                                              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		80.9
Translation
(A) 		1.5
Closure
(%) 		98.8
Bending Residues
( green ) 		  639 - 641
  661 - 667
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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