Ionotropic Glutamate Receptor 5

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Ionotropic Glutamate Receptor 5
  Conformer 1
(PDB) 		2f35 (A)
  Conformer 2
(PDB) 		1yae (F)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 135 1.15   7 - 108   213 - 250
2 77 1.19   109 - 212

Sequence


           _______________________________________________________________________________________________________________108______ 
 2f35(A) : ********RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQND-KGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILY 
         :                                                                                                                          
 1yae(F) : NITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELId----LAVAPLAITYVREK-iDFSKPFMTLGISILY 
           _______________________________________________________________________________________________________________536______ 

           _______________________________________________________________________________________________212______________________ 
 2f35(A) : RKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAI 
         :                                                                                                                          
 1yae(F) : -----------------iEYGAVEDGATMTFFk---------MWAFMSSRRQS-lVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAI 
           _______________________________________________________________________________________________760______________________ 

           ____________________                                                                                                     
 2f35(A) : LQLQEEGKLHMMKEKWWRGN                                                                                                     
         :                                                                                                                          
 1yae(F) : LQLQEEGKLHMMKEKWWR**                                                                                                     
           ____________________                                                                                                     

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		20.1
Translation
(A) 		0.6
Closure
(%) 		94.0
Bending Residues
( green ) 		  108 - 109
  212 - 213
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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