G Protein-Activated Inward Rectifier Potassium Channel 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name G Protein-Activated Inward Rectifier Potassium Channel 2
  Conformer 1
(PDB) 		3syq (A)
  Conformer 2
(PDB) 		3syp (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 194 0.63   57 - 85   185 - 188   192 - 194   203 - 375
2 94 0.58   86 - 184   189 - 191   195 - 202

Sequence


           ______________81________________________________________________________________________________________183________194_1 
 3syq(A) : IQRYVRKDGKCNVHH-----dIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAcVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKIS 
         :                                                                                                                          
 3syp(A) : IQRYVRKDGKCNVHHyRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAcVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKIS 
           ______________81________________________________________________________________________________________183________194_1 

           98______________________________________________________________________________________________________________________ 
 3syq(A) : QPKKAAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEA 
         :                                                                                                                          
 3syp(A) : QPKKAAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEA 
           98______________________________________________________________________________________________________________________ 

           _________________________________________________________________                                                        
 3syq(A) : TGMTCQARSSYITSEILWGYRFTPVLT----fYEVDYNSFHETYETSTPSLSAKELAELAN****                                                        
         :                                                                                                                          
 3syp(A) : TGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELANRAES                                                        
           _________________________________________________________________                                                        

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		8.5
Translation
(A) 		0.3
Closure
(%) 		43.1
Bending Residues
( green ) 		  81 - 89
  183 - 192
  194 - 195
  198 - 204
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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