Ketohexokinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Ketohexokinase
  Conformer 1
(PDB) 		6p2d (A)
  Conformer 2
(PDB) 		2hlz (B)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 257 0.84   6 - 17   35 - 100   114 - 295
2 30 0.65   18 - 34   101 - 113

Sequence


           _____________17______________33________________________________________________________________100________111___________ 
 6p2d(A) : EKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAPGHVADFLVADFRQRGVDVSQVTWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSA 
         :                                                                                                                          
 2hlz(B) : GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTILSLLGAPCAF-gS-aPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDVSA 
           _____________17______________33________________________________________________________________100________111___________ 

           ________________________________________________________________________________________________________________________ 
 6p2d(A) : KDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQSAVEALRGLYSRVKKGATLVCAWAEEGADALGPDGQLLHS 
         :                                                                                                                          
 2hlz(B) : TDFEKVDLTQFKWIHIEGRNASEQVK-lQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHS 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________                                                                 
 6p2d(A) : DAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV                                                                 
         :                                                                                                                          
 2hlz(B) : DAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV                                                                 
           ________________________________________________________                                                                 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		13.3
Translation
(A) 		-0.4
Closure
(%) 		77.8
Bending Residues
( green ) 		  17 - 18
  33 - 35
  100 - 101
  111 - 116
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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