DynDom - Protein Domain Motions

Receptor-Type Tyrosine-Protein Phosphatase Epsilon

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Receptor-Type Tyrosine-Protein Phosphatase Epsilon
Conformer 1 (PDB)	2jjd (C)
Conformer 2 (PDB)	2jjd (F)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	284	0.34	113 - 425
2	252	0.29	426 - 689

Sequence

`________________________________________________________________________________________________________________________` `2jjd(C) : KYFPIPVEHLEEEIRIRS--kQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLgIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVML` `:` `2jjd(F) : KYFPIPVEHLEEEIRIRSAcKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLgIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVML` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2jjd(C) : TNLKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPkAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQ` `:` `2jjd(F) : TNLKERKEEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPkAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQ` `________________________________________________________________________________________________________________________` `___________________________________________405__________________________________________________________________________` `2jjd(C) : KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSgLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMyTDYINASFIDGYRQKDYFIATQGP` `:` `2jjd(F) : KVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSgLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSM-tDYINASFIDGYRQKDYFIATQGP` `___________________________________________405__________________________________________________________________________` `________________________________________________________________________________________________________________________` `2jjd(C) : LAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNgEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNHPITV` `:` `2jjd(F) : LAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNgEQVRVVRQFHFHGWPEIGIPAEGKGMIDLIAAVQKQQQQTGNHPITV` `________________________________________________________________________________________________________________________` `_______________________________________________________________` `2jjd(C) : HCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID` `:` `2jjd(F) : HCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID` `_______________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	6.8
Translation (A)	0.0
Closure (%)	30.8
Bending Residues ( green )	405 - 426
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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