Serine/threonine-Protein Kinase 4

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Serine/threonine-Protein Kinase 4
  Conformer 1
(PDB) 		3com (A)
  Conformer 2
(PDB) 		3com (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 230 0.56   59 - 89   93 - 100   104 - 296
2 29 0.36   32 - 58   90 - 92   101 - 103

Sequence


           _____________________________________58_____________________________89_92_____100_______________________________________ 
 3com(A) : *************VFDVLEKLGgSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 
         :                                                                                                                          
 3com(B) : KLDEDSLTKQPEEVFDVLEKLGgSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEY 
           _____________________________________58_____________________________89_92_____100_______________________________________ 

           ________________________________________________________________________________________________________________________ 
 3com(A) : LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDmAKRNvIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQC 
         :                                                                                                                          
 3com(B) : LHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDmAKRNvIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQC 
           ________________________________________________________________________________________________________________________ 

           _______________________________________                                                                                  
 3com(A) : LVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAM**                                                                                  
         :                                                                                                                          
 3com(B) : LVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMDV                                                                                  
           _______________________________________                                                                                  

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		8.2
Translation
(A) 		0.3
Closure
(%) 		99.6
Bending Residues
( green ) 		  58 - 59
  89 - 90
  92 - 93
  100 - 101
  103 - 104
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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