DynDom - Protein Domain Motions

Tryptophanyl-Trna Synthetase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Tryptophanyl-Trna Synthetase
Conformer 1 (PDB)	2azx (A)
Conformer 2 (PDB)	1r6t (B)
Window Length	11
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	272	0.7	149 - 151 155 - 304 323 - 331 336 - 460
2	70	0.59	102 - 148 152 - 154 305 - 322 332 - 335

Sequence

`_____________________________________________________________146________________________________________________________` `2azx(A) : EDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDnQVLDAYENKKPFYLYTGRGPSSEAhVGHLIPFIFTKWLQDVFNVPLVIQtDDEKYLWK` `:` `1r6t(B) : **************GIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDnQVLDAYENKKPFYLYTGRGPSSEAhVGHLIPFIFTKWLQDVFNVPLVIQtDDEKYLWK` `_____________________________________________________________146________________________________________________________` `_______________________________________________________________________________________________304______________322_____` `2azx(A) : DLTLDQAYGDAVENAKDIIACGFDINKTFIFSDLDYgsSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRtRDVAPRI` `:` `1r6t(B) : DLTLDQAYGDAVENAKDIIACGFDINKTFIFSDLDYgsSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRtRDVAPRI` `_______________________________________________________________________________________________304______________322_____` `_331_335________________________________________________________________________________________________________________` `2azx(A) : GYPKPALLHSTFFPALQGAQTKsASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFyLTFFLEDDDKLEQIRKDYTSGAlTGELKKALIEVLQPLIAEHQARRK` `:` `1r6t(B) : GYPKPALLHSTFFPALQG--------pNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFyLTFFLEDDDKLEQIRKDYTSGAlTGELKKALIEVLQPLIAEHQARRK` `_331_335________________________________________________________________________________________________________________` `_________________` `2azx(A) : EVTDEIVKEFtPRKLSF` `:` `1r6t(B) : EVTDEIVKEFtPRKLA` `_________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	5.3
Translation (A)	0.0
Closure (%)	76.3
Bending Residues ( green )	146 - 155 304 - 305 322 - 323 331 - 332 335 - 336
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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