Udp-Galactose 4-Epimerase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Udp-Galactose 4-Epimerase
  Conformer 1
(PDB) 		1ek6 (A)
  Conformer 2
(PDB) 		4twr (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 283 1.84   7 - 224   236 - 292   310 - 336
2 28 1.32   225 - 235   293 - 309

Sequence


           ________________________________________________________________________________________________________________________ 
 1ek6(A) : MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 
         :                                                                                                                          
 4twr(A) : *ANNVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAV--------------RWGDFVEGDILDQARLVETMEKYAPVAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACR 
           ________________________________________________________________________________________________________________________ 

           _______________________________________________________________________________________________________224________235___ 
 1ek6(A) : AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGE--DPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGV 
         :                                                                                                                          
 4twr(A) : LTRTQNVIFSSSCATYGVPSRLPIGEGEAQNP-INPYGRTKLIAEHMLADYAVA-YGLRYVALRYFNASGADIDGELGEKHDPE---THLIPRAMMAAAGRLDVLEVYGDDYETPDGTCI 
           _______________________________________________________________________________________________________208________219___ 

           ___________________________________________________292______________309______________________________________            
 1ek6(A) : RDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEELGW-TAALGLDRMCEDLWRWQKQNPSGFGT            
         :                                                                                                                          
 4twr(A) : RDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALAAEKLGFHTVYSDLDTIIRTAAPHFGLEVR****            
           ___________________________________________________276______________293______________________________________            

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		21.5
Translation
(A) 		0.3
Closure
(%) 		76.2
Bending Residues
( green ) 		  224 - 225
  235 - 237
  292 - 294
  309 - 310
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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