Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		6pnx (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 184 1.45   538 - 545   563 - 640   646 - 646   656 - 760
2 99 1.77   468 - 537   546 - 562   641 - 645   647 - 655

Sequence


           __________________________________________________________________________537_____545______________562__________________ 
 3gqi(A) : ***ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPG 
         :                                                                                                                          
 6pnx(B) : SELELPADPKWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPG 
           __________________________________________________________________________531_____539______________556__________________ 

           _________________________________________________________640____________________________________________________________ 
 3gqi(A) : LEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHID--kKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSP 
         :                                                                                                                          
 6pnx(B) : LD--------pEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDEVYTHQSDVWSFGVLLWEIFTLGGSP 
           _________________________________________________________634____________________________________________________________ 

           _____________________________________________________________________                                                    
 3gqi(A) : YPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                    
         :                                                                                                                          
 6pnx(B) : YPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTS*******                                                    
           _____________________________________________________________________                                                    

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		19.7
Translation
(A) 		-0.1
Closure
(%) 		95.5
Bending Residues
( green ) 		  537 - 538
  545 - 546
  562 - 563
  640 - 662
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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