Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		4r6v (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 170 1.39   541 - 545   564 - 644   663 - 759
2 89 2.03   466 - 540   546 - 563   645 - 645

Sequence


           ____________________________________________________________________________________540__545_______________563__________ 
 3gqi(A) : **********ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL 
         :                                                                                                                          
 4r6v(A) : DPLLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMdQ-----ASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVILECAAKGNLREFL 
           ____________________________________________________________________________________529__534_______________552__________ 

           ________________________________________________________________640_____________________________________________________ 
 3gqi(A) : QARRPPGLEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT 
         :                                                                                                                          
 4r6v(A) : RARRPPg----------P---LSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLA---------------pVKWMAPEALFDEVYTHQSDVWSFGILLWEIFT 
           ________________________________________________________________629_____________________________________________________ 

           __________________________________________________________________________                                               
 3gqi(A) : LGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                               
         :                                                                                                                          
 4r6v(A) : LGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV********                                               
           __________________________________________________________________________                                               

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		17.1
Translation
(A) 		-0.5
Closure
(%) 		99.1
Bending Residues
( green ) 		  540 - 541
  545 - 546
  563 - 564
  640 - 664
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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