Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Basic Fibroblast Growth Factor Receptor 1
  Conformer 1
(PDB) 		3gqi (A)
  Conformer 2
(PDB) 		5nud (B)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 143 0.81   565 - 576   604 - 604   607 - 754
2 101 2.55   471 - 564   585 - 603   605 - 606

Sequence


           _______________________________________________________________________________________________________564______573_____ 
 3gqi(A) : *****ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRP 
         :                                                                                                                          
 5nud(B) : PLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRP 
           _______________________________________________________________________________________________________553______562_____ 

           ________________________________________________________________________________________________________________________ 
 3gqi(A) : PGLEFSFNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDkKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSP 
         :                                                                                                                          
 5nud(B) : PpLSFPV--------------LVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADF----------------rLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSP 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________                                                    
 3gqi(A) : YPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQElDLS                                                    
         :                                                                                                                          
 5nud(B) : YPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV********                                                    
           _____________________________________________________________________                                                    

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		17.2
Translation
(A) 		-1.0
Closure
(%) 		99.4
Bending Residues
( green ) 		  564 - 567
  573 - 607
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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