Beta 2 Adrenergic Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Beta 2 Adrenergic Receptor
  Conformer 1
(PDB) 		6kr8 (A)
  Conformer 2
(PDB) 		3ny8 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 196 2.44   34 - 229
2 23 2.68   317 - 339

Sequence


           ________________________________________________________________________________________________________________________ 
 6kr8(A) : EVWVVGMGIVMSLIVLAIVFGNVLVITAICKFERLQTVTNYFITSLAVADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAICSPFKYQSLLTKCK 
         :                                                                                                                          
 3ny8(A) : **WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQSLLTKNK 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________229________________________________________ 
 6kr8(A) : ARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQ-----KIDKSEG-RFHVQNVSQVEQDGRTGHGHRRSSK 
         :                                                                                                                          
 3ny8(A) : ARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAEETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLNIFEMLRID--EGLRLKIYKDTEGYYTIGIGHLLTKSPS 
           _____________________________________________________________________________229________________________________________ 

           ________________________________________________________________________________________________________________________ 
 6kr8(A) : FACKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYSRSPDFRCAFQELLA****************************************** 
         :                                                                                                                          
 3ny8(A) : LNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTW 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________________________________________                                      
 6kr8(A) : ***********************************************************************************                                      
         :                                                                                                                          
 3ny8(A) : DAYKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCL                                      
           ___________________________________________________________________________________                                      

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		132.9
Translation
(A) 		21.5
Closure
(%) 		13.2
Bending Residues
( green ) 		  229 - 318
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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