Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (A)
  Conformer 2
(PDB) 		1tt1 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 140 1.42   7 - 109   218 - 254
2 105 1.32   110 - 217

Sequence


           ________________________________________________________________________________________________________109_____________ 
 1fto(A) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1tt1(A) : NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGTPID 
           ________________________________________________________________________________________________________109_____________ 

           ____________________________________________________________________________________________217_________________________ 
 1fto(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
         :                                                                                                                          
 1tt1(A) : SADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQ 
           ____________________________________________________________________________________________214_________________________ 

           ___________________                                                                                                      
 1fto(A) : EQGLLDKLKNKWWYDKGEC                                                                                                      
         :                                                                                                                          
 1tt1(A) : EEGKLHMMKEKWWR*****                                                                                                      
           ___________________                                                                                                      

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		23.2
Translation
(A) 		0.4
Closure
(%) 		96.2
Bending Residues
( green ) 		  109 - 110
  217 - 218
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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