Ionotropic Glutamate Receptor 5

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Ionotropic Glutamate Receptor 5
  Conformer 1
(PDB) 		2f35 (A)
  Conformer 2
(PDB) 		2i0c (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 140 0.77   6 - 107   215 - 252
2 107 0.58   108 - 214

Sequence


           _______________________________________________________________________________________________________107______________ 
 2f35(A) : *RTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQND-KGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTPID 
         :                                                                                                                          
 2i0c(A) : NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITCVREKVIDFSKPFMTLGISILYRKGTPID 
           _______________________________________________________________________________________________________108______________ 

           _______________________________________________________________________________________211______________________________ 
 2f35(A) : SADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEG 
         :                                                                                                                          
 2i0c(A) : SADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAICQLQEEG 
           _______________________________________________________________________________________212______________________________ 

           _________________                                                                                                        
 2f35(A) : KLHMMKEKWWRGN****                                                                                                        
         :                                                                                                                          
 2i0c(A) : KLHMMKEKWWRGNGCPS                                                                                                        
           _________________                                                                                                        

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		30.2
Translation
(A) 		0.9
Closure
(%) 		100.0
Bending Residues
( green ) 		  107 - 110
  211 - 215
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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