DynDom - Protein Domain Motions

Importin Subunit Alpha-3

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Importin Subunit Alpha-3
Conformer 1 (PDB)	6bvz (A)
Conformer 2 (PDB)	6wx8 (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	81	0.87	200 - 257 262 - 272 275 - 278 283 - 287 310 - 312
2	126	0.93	74 - 199
3	203	0.73	258 - 261 273 - 274 279 - 282 288 - 309 313 - 483

Sequence

`________________________________________________________________________________________________________________________` `6bvz(A) : ****SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIG` `:` `6wx8(A) : RVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIG` `________________________________________________________________________________________________________________________` `__________199_______________________________________________________257____________272___278_282__287___________________` `6bvz(A) : DGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALR` `:` `6wx8(A) : DGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALR` `__________199_______________________________________________________257____________272___278_282__287___________________` `309_____________________________________________________________________________________________________________________` `6bvz(A) : AVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQ` `:` `6wx8(A) : AVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQ` `309_____________________________________________________________________________________________________________________` `____________________________________________________________` `6bvz(A) : VVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFS` `:` `6wx8(A) : VVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFF` `____________________________________________________________`

Morph

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Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	18.9
Translation (A)	-0.3
Closure (%)	66.9
Bending Residues ( green )	199 - 200
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	12.3
Translation (A)	-0.4
Closure (%)	30.0
Bending Residues ( green )	257 - 262 272 - 275 278 - 279 282 - 283 287 - 288 309 - 310 312 - 314
Bending Region Analysis