Proton-Gated Ion Channel

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Proton-Gated Ion Channel
  Conformer 1
(PDB) 		4hfi (A)
  Conformer 2
(PDB) 		4npq (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 168 1.57   114 - 127   159 - 184   186 - 313
2 132 0.6   7 - 113   128 - 151   185 - 185

Sequence


           __________________________________________________________________________________________________________113___________ 
 4hfi(A) : VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 
         :                                                                                                                          
 4npq(C) : VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 
           __________________________________________________________________________________________________________113___________ 

           127____________________150_________________________178__________________________________________________________________ 
 4hfi(A) : TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVET 
         :                                                                                                                          
 4npq(C) : TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVET 
           127____________________150_________________________178__________________________________________________________________ 

           _______________________________________________________________________                                                  
 4hfi(A) : NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF                                                  
         :                                                                                                                          
 4npq(C) : NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVFLLANIILAFLFF                                                  
           _______________________________________________________________________                                                  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		10.3
Translation
(A) 		-0.7
Closure
(%) 		25.7
Bending Residues
( green ) 		  113 - 114
  127 - 128
  150 - 159
  178 - 186
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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