Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Pyruvate Kinase
  Conformer 1
(PDB) 		1e0t (A)
  Conformer 2
(PDB) 		1e0u (B)
  Window Length 13
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 330 0.47   7 - 65   68 - 68   171 - 464
2 104 0.37   66 - 67   69 - 170

Sequence


           _______________________________________________________________65_______________________________________________________ 
 1e0t(A) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
         :                                                                                                                          
 1e0u(B) : MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVG 
           _______________________________________________________________65_______________________________________________________ 

           ______________________________________________169_______________________________________________________________________ 
 1e0t(A) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
         :                                                                                                                          
 1e0u(B) : NTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGI 
           ______________________________________________169_______________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1e0t(A) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATM---------rPTDAEAGDVANAILDGTDAVMLSGE------pLEAVSIMATICERTDRVMNSRLEiTEAVCRGAVETAEKL 
         :                                                                                                                          
 1e0u(B) : MVARGDLGVEIPVEEVIFAQKMMIEKCIRALKVVITATMMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEiTEAVCRGAVETAEKL 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________________________________                    
 1e0t(A) : DAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                    
         :                                                                                                                          
 1e0u(B) : DAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL                    
           _____________________________________________________________________________________________________                    

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		3.2
Translation
(A) 		-0.3
Closure
(%) 		46.3
Bending Residues
( green ) 		  65 - 70
  169 - 171
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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