Serine/threonine-Protein Kinase Pak 4

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Serine/threonine-Protein Kinase Pak 4
  Conformer 1
(PDB) 		2cdz (A)
  Conformer 2
(PDB) 		2f57 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 209 0.82   354 - 357   362 - 379   398 - 585
2 73 1.04   301 - 353   358 - 361   380 - 397

Sequence


           _____________________________________________________________353_____361______________378________________397____________ 
 2cdz(A) : *********VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVR--gKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTH 
         :                                                                                                                          
 2f57(A) : NLYFQSMSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTH 
           _____________________________________________________________481_____489______________506________________525____________ 

           ________________________________________________________________________________________________________________________ 
 2cdz(A) : TRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKlVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDN 
         :                                                                                                                          
 2f57(A) : TRMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKlVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDS 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________                                                             
 2cdz(A) : LPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRT                                                             
         :                                                                                                                          
 2f57(A) : LPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQ***                                                             
           ____________________________________________________________                                                             

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		21.4
Translation
(A) 		0.1
Closure
(%) 		88.0
Bending Residues
( green ) 		  353 - 358
  361 - 366
  378 - 380
  397 - 399
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download