DynDom - Protein Domain Motions

Thermosome Alpha Subunit

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Thermosome Alpha Subunit
Conformer 1 (PDB)	1q3q (A)
Conformer 2 (PDB)	3ko1 (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	356	1.62	23 - 220 353 - 357 370 - 522
2	144	2.22	221 - 352 358 - 369

Sequence

`________________________________________________________________________________________________________________________` `1q3q(A) : VVILPEGTQRYVGRDAQRLNILAARIIAETVRTTLGPKGMDKMLVDSLGDIVVTNDCATILDKIDLQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLRKAEELLDQNIHPSIITKGY` `:` `3ko1(A) : **********GKEAVRANIAAVKAVEEALKSTYGPRGMDKMLVDSLGDITITNDGATILDKMDLQHPAAKLLVQIAKGQDEETADGTKTAVIFSGELVKKAEDLLYKDVHPTIIISGY` `________________________________________________________________________________________________________________________` `_________________________________________________________________________________________220____________________________` `1q3q(A) : ALAAEKAQEILDEIAIRVDPDDEETLLKIAATSITGKNAESHKELLAKLAVEAVKQVAEKKDGKYVVDLDNIKFEKKAGEGVEESELVRGVVIDKEVVHPRMPKRVENAKIALINEALEV` `:` `3ko1(A) : KKAEEVALQTIQELAQTVSINDTDLLRKIAMTSLSSKAVAGAREYIADIVVKAVTQVAELRGDKWYVDLDNIQIVKKAGGSINDTQLVYGIVVDKEVVHPGMPKRLENAKIALIDASLEV` `_________________________________________________________________________________________227____________________________` `_____________________________________________________________________________________________________352_356________367_` `1q3q(A) : KKTETDAKINITSPDQLMSFLEQEEKMLKDMVDHIAQTGANVVFVQKGIDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVKDLTPEDLGYAEVVEERKLAGENMIFVEGCKN` `:` `3ko1(A) : EKPELDAEIRINDPTQMQKFLDEEENLIKEKVDKILATGANVIICQKGIDEVAQSYLAKKGVLAVRRAKKSDLEKLARATGGRVVSNIDEISEQDLGYASLIEERKVGEDKMVFVEGAKN` `_____________________________________________________________________________________________________359_363________374_` `________________________________________________________________________________________________________________________` `1q3q(A) : PKAVTILIRGGTEHVIDEVERALEDAVKVVKDVMEDGAVLPAGGAPEIELAIRLDEYAKQVGGKEALAIENFADALKIIPKTLAENAGLDTVEMLVKVISEHKNRGLG-IGIDVFEGKPA` `:` `3ko1(A) : PKSISILIRGGLERLVDETERALRDALGTVADVIKDGRAIAGGGAVEIEIAKKLRKYAPQVGGKEQLAVEAYANALESLVSILIENAGFDPIDLLMKLRSTHENENNKWYGIDLYAGQPV` `________________________________________________________________________________________________________________________` `_______________________________________` `1q3q(A) : DMLEKGIIEPLRVKKQAIKSASEAAIMILRIDDVIAAKA` `:` `3ko1(A) : DMWQKGVIEPALVKMNAIKAATEAATLVLRIDDVVSA` `_______________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	24.9
Translation (A)	0.3
Closure (%)	10.6
Bending Residues ( green )	220 - 221 352 - 353 356 - 358 367 - 370
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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