Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor 2
  Conformer 1
(PDB) 		4u2r (B)
  Conformer 2
(PDB) 		1fto (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 146 0.66   7 - 108   194 - 200   220 - 256
2 107 0.44   109 - 193   201 - 219   257 - 259

Sequence


           _________________________________________________________________________________________________________108____________ 
 4u2r(B) : GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTP 
         :                                                                                                                          
 1fto(A) : ****TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTP 
           _________________________________________________________________________________________________________108____________ 

           ______________________________________________________________________193____200______________217_______________________ 
 4u2r(B) : IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLK 
         :                                                                                                                          
 1fto(A) : IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLK 
           ______________________________________________________________________193____200______________217_______________________ 

           _____________256_______                                                                                                  
 4u2r(B) : LSEQGVLDKLKNKWWYDKGECGS                                                                                                  
         :                                                                                                                          
 1fto(A) : LNEQGLLDKLKNKWWYDKGEC**                                                                                                  
           _____________256_______                                                                                                  

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		7.0
Translation
(A) 		-0.3
Closure
(%) 		91.8
Bending Residues
( green ) 		  108 - 111
  193 - 194
  200 - 201
  217 - 220
  256 - 257
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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