Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Metabotropic Glutamate Receptor Subtype 1
  Conformer 1
(PDB) 		1ewv (A)
  Conformer 2
(PDB) 		1ewv (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 274 0.69   38 - 207   344 - 476
2 170 0.81   208 - 343   477 - 510

Sequence


           ________________________________________________________________________________________________________________________ 
 1ewv(A) : RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRkPIAGVIGPGSSSVAIQVQNLLQLFDIPQIA 
         :                                                                                                                          
 1ewv(B) : RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRkPIAGVIGPGSSSVAIQVQNLLQLFDIPQIA 
           ________________________________________________________________________________________________________________________ 

           ____________________207_________________________________________________________________________________________________ 
 1ewv(A) : YSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMR 
         :                                                                                                                          
 1ewv(B) : YSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMR 
           ____________________207_________________________________________________________________________________________________ 

           ____________________________________343_________________________________________________________________________________ 
 1ewv(A) : RLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGL 
         :                                                                                                                          
 1ewv(B) : RLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGL 
           ____________________________________343_________________________________________________________________________________ 

           _________________________________________________476____________________________________                                 
 1ewv(A) : QNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                                 
         :                                                                                                                          
 1ewv(B) : QNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                                 
           _________________________________________________476____________________________________                                 

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		26.7
Translation
(A) 		1.1
Closure
(%) 		97.3
Bending Residues
( green ) 		  207 - 212
  343 - 344
  476 - 481
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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