Orotate Phosphoribosyltransferase 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Orotate Phosphoribosyltransferase 1
  Conformer 1
(PDB) 		2pry (A)
  Conformer 2
(PDB) 		2ps1 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 160 1.77   5 - 19   39 - 162   167 - 196
2 51 1.61   4 - 4   20 - 38   163 - 166   197 - 223

Sequence


           __4_____________19_________________38___________________________________________________________________________________ 
 2pry(A) : IMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEA------gIIVGSA 
         :                                                                                                                          
 2ps1(A) : IMLEDYQKNFLELAIECQALRFGSFKLKSGRESPYFFNLGLFNTGKLLSNLATAYAIAIIQSDLKFDVIFGPAYKGIPLAAIVCVKLAEIGGSKFQNIQYAFNRKEAKDHGEGGIIVGSA 
           __4_____________19_________________38___________________________________________________________________________________ 

           ______________________________________162_166___________________________196_____________________________                 
 2pry(A) : LENKRILIIDDVMTa---INEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGASA                 
         :                                                                                                                          
 2ps1(A) : LENKRILIIDDVMTAGTAINEAFEIISNAKGQVVGSIIALDRQEVVSTDDKEGLSATQTVSKKYGIPVLSIVSLIHIITYLEGRITAEEKSKIEQYLQTYGASA                 
           ______________________________________162_166___________________________196_____________________________                 

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		22.2
Translation
(A) 		0.3
Closure
(%) 		99.5
Bending Residues
( green ) 		  4 - 5
  19 - 20
  38 - 39
  162 - 163
  166 - 167
  196 - 197
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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