Tight Junction Protein Zo-1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Tight Junction Protein Zo-1
  Conformer 1
(PDB) 		3tsw (A)
  Conformer 2
(PDB) 		3shw (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 180 0.87   423 - 641   799 - 800
2 144 0.64   642 - 798

Sequence


           ________________________________________________________________________________________________________________________ 
 3tsw(A) : MILRPSMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGL 
         :                                                                                                                          
 3shw(A) : *****SMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGL 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________639_____________________________________________________ 
 3tsw(A) : SFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQ----kFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKS---iIRLHTIKQIIDQDK 
         :                                                                                                                          
 3shw(A) : SFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTqTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEPgIIRLHTIKQIIDQDK 
           ________________________________________________________________639_____________________________________________________ 

           ____________________________________________________________________________________________797______                    
 3tsw(A) : HALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEG                    
         :                                                                                                                          
 3shw(A) : HALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSE*                    
           ____________________________________________________________________________________________797______                    

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		19.1
Translation
(A) 		0.1
Closure
(%) 		89.1
Bending Residues
( green ) 		  639 - 642
  797 - 799
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download