Topoisomerase IV Subunit B

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Topoisomerase IV Subunit B
  Conformer 1
(PDB) 		1s16 (A)
  Conformer 2
(PDB) 		3lps (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 185 1.81   1017 - 1218
2 158 1.3   1219 - 1377

Sequence


           ________________________________________________________________________________________________________________________ 
 1s16(A) : TYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALS 
         :                                                                                                                          
 3lps(A) : ***********GLDPVKRRPGMYTDTARPNHLAQEVIDNSVDEALAGHAKQIEVTLYKDGSCEVSDDGRGMPVDIHPEEKIPGVELILTRlH-----------------GVGVSVVNALS 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________1215____________________________ 
 1s16(A) : KRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRNTGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIGNFA 
         :                                                                                                                          
 3lps(A) : TKVELFIKREGSEHRMEFRDGNAASKLEVVGTVGKKNTGTRLRFWADPKYFDTPKFNVRALRHLLRAKAVLCPGLTVKLHDEATGEQDSWYFENGLRDYLKGEMAEHEMLPADLFVGSLK 
           _________________________________________________________________________________________259____________________________ 

           ________________________________________________________________________________________________________________________ 
 1s16(A) : GDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQ 
         :                                                                                                                          
 3lps(A) : KDTEIVDWAAGWVPEG-ELVQESYVNLIPTAQHGTHVNGLRSGLTDALREFCDFRNLLPRGVKLAPEDVWDRVTFVLSLKMTDPQFSGQTKERLSSRQAAGFIEGAAHDAFSLYLNQNVE 
           ________________________________________________________________________________________________________________________ 

           ____________________                                                                                                     
 1s16(A) : AAELLAEMAISSAQRRMRAA                                                                                                     
         :                                                                                                                          
 3lps(A) : IGEKIAQIAIDRASAR****                                                                                                     
           ____________________                                                                                                     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		23.7
Translation
(A) 		-0.9
Closure
(%) 		83.6
Bending Residues
( green ) 		  1215 - 1219
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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